Brain Science Daily: The desire for food during pregnancy comes from dopamine secreted by the brain

1. Molecular Psychiatry | He Yong and Xia Mingrui team and collaborators reveal the molecular mechanism of the gradient disorders of the depression brain function connection group

Source: Beishi Brain and Cognitive Science

Elertarctification of severe depression disorders brain function-associated with gene expression diagram of gradient abnormal mode and gene expression map

Recently, Molecular Psychiatry has published research papers of He Yong and Xia Mingrui teams in the National Key Laboratory of Beijing Normal University.This study comprehensively adopts the multi-center big data and human brain specimen gene expression data of adolescents and adults’ static static function, and found that the global indicators of the primary cortex-combined cortex gradient of depression are significantly lower than the health control, and the adolescent period starts from the adolescence period.The gradient indicators of the patient are significantly lower than those of patients from adults.

The study revealed that the abnormal mode of the local gradient score is significantly related to the expression of related genes such as transmissions signal and calcium ion binding, explaining the potential molecular mechanism of depression brain connection gradient disorders, not only to understand the brain network of depression.The damage mechanism provides a new perspective, and it is also important for the establishment of clinical appropriate clinical efficacy assessment logo.

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Molecular Psychiatry | He Yong and Xia Mingrui team and collaborators reveal the molecular mechanism of the gradient disorders of the depression brain function connection group

2. SCI ADV | Wang Yanjiang team and others found that blood soluble CD22 is related to AD patients in patients with Aβ deposition and cognitive loss

Source: bioartMed

As the main immune cells in the brain, small glue cells have functions such as removing metabolic products, pathological substances and cell fragments in the brain, and play an important role in maintaining the stability of the internal environment of the brain.CD22 is one of the members of the receptor family of salivary acidic galvin -like condensate, and has an immunosuppressive function.Recent research has found that reducing the expression of CD22 can enhance the β phagocytic function of the elderly mouse gel cells and alleviate age -related cognitive reduction.The soluble CD22 (SCD22) released by CD22 is cut released by cutting is the main form of CD22 to play biological activity.

Recently, the Wang Yanjiang team of the Department of Neurology of Daping Hospital of the Army Military Medical University and COLIN L. Masters, the University of Melbourne, Australia, published research on research on Science Advances magazines.The study of the cross -sectional crowd of Chongqing Aging and dementia research queue and the vertical queue of Australian images, biomarkers and lifestyle studies, found that the level of plasma SCD22 is related to the progress of AD core biomarkers and diseases. It is prompted as potential ADBiomagotherapy.The research supports CD22 may play a role in AD, and the specific mechanism needs to be further explored.

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SCI ADV | Wang Yanjiang team and others found that blood -soluble CD22 is related to AD patients in patients with Aβ deposition and cognitive decline in the brain of AD

3. Nature sub -magazine: The desire for food during pregnancy comes from the dopamine secreted by the brain

Source: Biological World

Although the desire for cheerful food is a common feature of pregnancy and may cause weight gain or even obesity, the principles of neurological biology are still unclear.Recently, researchers at the University of Barcelona, Spain published research papers in Nature Metabolism.The mouse research shows that the food desire during pregnancy is driven by the dopamine signal in the brain reward system.These preliminary research results also show that this kind of diet or has long -term metabolic impact on future generations, which brings new revelations to the neurons -based basis of the desire of food -related food.

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Nature sub -magazine: The desire for food during pregnancy comes from dopamine secreted by the brain

4. How can I break the liver, wounds, and wounds, how can I break it?Research on Southwest University: Drinking tea may relieve

Source: China Biotechnology Network

The rhythm of day and night is an endogenous chronograph (biological clock). It takes about 24 hours as a cycle. It controls a series of biological processes of the body and at the same time induces our rhythmic natural behavior.Day and night rhythm disorders affect the body’s metabolic and inflammatory response through multi-organ disturbance (intestinal-liver-brain shaft, etc.).However, rare mechanisms about the interaction between them still know.Recently, published in a review on Critical Reviews in Food Science and Nutrition, Professor Zeng Liang from the School of Food Sciences, School of Food Science, School of Food Science, from Southwest University, analyzed it.One of the key factors of disorders and increased neuritis, tea may interfere with bile acid metabolism, chromine metabolism, and G protein coupling (GPCR), thereby reducing metabolic disorders and inflammation caused by rhythm disorders of day and night. Among themX receptor (FXR), aromatics (AHR) and GPCR may be potential targets.

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How can I break up late and hurt the liver, wounds, and wounds?Research on Southwest University: Drinking tea may relieve

5, STTT | Zhou Penghui and other teams of Sun Yat -sen University found the endogenous marijuana system.

Source: Inature

The combination of immune examination point blocking (ICB) and chemotherapy has significantly improved the clinical benefits of cancer treatment.Because chemotherapy is usually related to adverse events, it is often used in combined therapy to accompany the treatment of drugs that control the side effects of chemotherapy.However, whether these auxiliary drugs will hinder immune therapy still unknown.Recently, Zhou Penghui, Sun Yat -sen University, and Li Wende, the Guangdong Experimental Animal Monitoring Institute, jointly published research papers online at Signal Transduted and Targeted therapy.The study found that Δ9-tetrahydrocular phenol (THC) is a key component that approves the disgusting drugs caused by chemotherapy, which reduces the treatment effect of the PD-1 blocking agent.Anandamide (AEA) of endogenous marijuana also hinders anti -tumor immunity, indicating that the endogenous cannabis system (ECS) has an immunosuppressive effect.The results revealed the new mechanism of ECS -mediated T -cell anti -cancer immunity, and it is recommended that marijuana and marijuana drugs should be avoided during immunotherapy.

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STTT | Zhou Penghui and other teams of Sun Yat -sen University found that the endogenous cannabis system has an immunosuppressive effect. During immunotherapy, use marijuana drugs should be avoided

6. George Asia Research Institute developed probiotic treatment of Parkinson’s disease, which can synthesize L -Ring Daba in the patient’s body. The dose is controllable and has no side effects

Source: Shenghui Synbio

The method of transforming probiotics to produce L-DOPA Parkinson’s disease (PD) is a gradual brain disease. The root cause of this disease is the brain black dopamine neuronal lesions, which leads to sufficient dopamine.The treatment method is limited to help patients control symptoms.In the treatment of drugs, Levota is a dopamine anterior body and is the most effective drug so far.

Recently, Professor Kanthasamy’s team of George Asia Research Institute used the newly developed synthetic biology and genetic engineering technology to use the reorganized 4-HYDROPHENYLACETATATATE 3-Monooxygenase and FAD enzyme gene to transform the probiotics in the intestine.This kind of engineering probiotics are safe and resistant to tolerance. It can use the tyrosine produced by the human body to synthesize Laosaiba, which is equivalent to letting Parkinson patients produce drugs.This method can highly adjust the output of Laotaco and provide personal doses for each patient.This treatment method can eliminate the side effects caused by Laoto Dapa to the brain’s discontinuous transportation, which is of great significance to improve the treatment level of Parkinson’s patients.The research results were published on Neuroscience News.

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Georgia Research Institute developed probiotics for Parkinson’s disease, which can synthesize L -Ring Daba in the patient’s body.

7, BMJ: Note!The stomach reunion and right Metomi we often use will greatly increase the risk of ischemic stroke!

Source: New Frontier of Nervous

Studies emphasize the risk of ischemic strokes of anti -psychiatric drugs using the central effect, especially in the risk of elderly patients and dementia patients.Although anti -psychiatric drugs can also block various other receptors, the mechanism of these drugs may cause a stroke mechanism to be related to this dopamine antagonistic effect.At present, there is a lack of research on dopamine receptor antagonists, such as anti -dopamine antibiotics (ADA) stroke risks.Recently, French researchers used data from France’s reimbursement medical system database SNDS from France to conduct a case-time-comparison research.The results were published in BMJ magazines and found that the risk of recent use of ADA ischemia in ischemic stroke increased.Among them, the risk of academic and metharine is the greatest.

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BMJ: Note!The stomach reunion and right Metomi we often use will greatly increase the risk of ischemic stroke!

8. How do people use the media to deal with stress?

Source: Lei Li and students

From the perspective of evolution, stress can help individuals adapt to the environment, but the pressure that does not get effective in the long run will have a negative impact on individual health and well -being.A recent study published on the Communication Research discussion how people use the media to deal with stress.Pressure is a process of interaction between people and environment. The media is a kind of response tool to help the implementation of strategic implementation. The individual first needs to evaluate and make a choice of strategies. Later, according to the response strategy assessment and select the corresponding coping tools.If an individual’s use of a certain media is very active in daily life, when facing stress, you may unconsciously choose this behavior to deal with stress.

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How do people use the media to deal with stress?

Review: SIMON

Title: Photo Network

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